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Search Results for " cgamp synthase "

Targets

3

Compounds

1

Natural Products

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T10065 2',3'-cGAMP 2'-3'-cyclic GMP-AMP STING , cGAS
2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a second messenger in cellular innate immunity and is catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. 2',3'-cGAMP binds to STING to form a dimer, inducing the produc...
T38328 CU-32
CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS; IC50= 0.45 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS ...
T36985 Cyclic di-UMP (sodium salt)
Cyclic di-UMP is a pyrimidine-containing cyclic dinucleotide (CDN).1It is produced by bacterial cGAS/DncV-like nucleotidyltransferases (CD-NTases), such as LpCdnE02 fromL. pneumophila, and binds to cGAS, in the apo or ds...
Cat No. Product Name Synonyms Targets
T10065L 2',3'-cGAMP sodium 2'-3'-cyclic GMP-AMP sodium STING , cGAS
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium), a cGAMP synthase (cGAS) affecting cytoplasmic DNA production as a second messenger, is a transmembrane bridging protein that is a key component of the cellular innate imm...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01166 CGAS Protein, Human, Recombinant (His) Human E. coli
CGAS Protein, Human, Recombinant (His) is expressed in E. coli.
TargetMol